A confocal microscope is a type of microscope in which a thick object such as the cornea is illuminated with a focused spot of light the same microscope objective that is used to illuminate a point p1 in the object is used to collect the scattered and reflected light from same point p1. Confocal microscopy of the cornea is one of the modern methods of investigation allows to conduct intravital monitoring of the cornea state with visualization of tissues at the cellular and microstructural level this method due to the original design of the microscope and its high resolution . Abstract in vivo scanning slit confocal microscopy offers improved resolution and has resulted in new discoveries of corneal pathology at the cellular levelthe ability to provide high resolution real time images of the full thickness of theliving human cornea gives the clinician and the researcher an important new tool