Chanisms of all these conditions is protein misfolding aggregation hence the term protein folding disorders which can trigger cascades of events ultimately resulting in synapse loss and neuron death with devastating clinical consequences in many of the most precious spheres of human existence including personality cognition. Protein folding and misfolding neurodegenerative diseases editors ovadi judit orosz ferenc eds free preview. Protein folding and misfolding neurodegenerative diseases focus on structural biology 9781402094330 medicine health science books amazoncom. Protein folding and misfolding neurodegenerative diseases focus on structural biology by judit ovadi ferenc orosz publisher springer number of pages 274 publication date 2009 02 01 isbn 10 asin 1402094337 isbn 13 ean 9781402094330 binding hardcover product description the worldwide increasing age of populations brought the neurodegenerative diseases into the focus of interest. This special issue includes fifteen reviews and two original research articles by leading scientists in the fields of neuropathology biochemistry and cell biology dealing with the role of protein aggregation and prion like propagation of protein misfolding in neurodegenerative diseases