After carious stimulation odontoblasts initiate an inflammatory reaction by producing chemokines and synthesise a protective tertiary dentine after the destruction of these cells the pulp still has a high capacity to synthesise this tertiary dentine thanks to the presence of adult stem cells within the pulp. Suggested citationpathology of dental cariesnational research council 1952 a survey of the literature of dental carieswashington dc the national academies press doi 1017226 21295. Request pdf on jan 1 2008 o fejerskov and others published pathology of dental caries find read and cite all the research you need on researchgate. This monograph on dental caries is based on the special pathology of the tissues concerned the author rightly states a correct knowledge and understanding of normal structures is a fundamental requirement for the study of their pathological changes