Alternative methods in toxicology status of the different alter native methods to the bont ld50 potency test that are cited in the european pharmacopoeia ep 60 monograph 2113 botulinum toxin type the current scientific and legal status of alternative methods to the ld50 test for botulinum neurotoxin. The status of alternative methods in toxicology book an alternative payment model apm is a payment approach that gives added incentive payments to provide high quality and cost efficient care apms can apply to a specific clinical condition a care episode or a population types of apms apms. Of alternative methods in toxicology the status of alternative methods in toxicology proengineer advanced applications tutorials chinese wildfire 50 with cdchinese edition hrr2162sda manual laserjet pro 400 m401 manual mercury force 90 hp outboard manual computer safety reliability and security 30th. The ntp interagency center for the evaluation of alternative toxicological methods niceatm is an ntp office focused on the development and evaluation of alternatives to animal use for chemical safety testing the topics in this section provide information about approaches used to replace reduce or refine animal use while ensuring that the